GTX-11 attenuates lung fibrosis, inflammation and vascular remodeling in preclinical models of lung fibrotic disease.

Treatment with TGFβ upregulated MMP1 secretion, and GTX-11m showed a trend to reduce it (IPF p = 0.160, sarcoidosis p = 0.309, HP p = 0.059, control p = 0.144) ( Figure 5C ).

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