Barely Significant
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Association of SMAD4 gene polymorphisms with human papillomavirus infection and risk of cervical cancer: a case-control study.

BMC Cancer · 2026 · PMC12888450 · PMID 41530702

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In contrast, the distribution differences of rs8084630 across genotypes and genetic models did not reach statistical significance, suggesting this locus may not be a genetic factor influencing cervical cancer development in the study population.

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marginally significantno p-value reported
The T allele frequency was higher in the case group, showing a marginally significant negative correlation with cervical cancer risk.

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