Integrated analysis of DNA methylation and gene expression in dairy cows during early pregnancy.

BMC Genomics · 2026 · PMC12888507 · PMID 41527033

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an overall trendno p-value reported

14 E) There was an overall trend of hypomethylation, which is consistent with the results described in “Certification of differential methylation regions” section.

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did not reach statistical significanceno p-value reported

Although they did not reach statistical significance (FDR ≥ 0.05), some studies have found that these pathways are enriched during embryonic development in goats and cattle [ 37 , 38 ].

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an obvious trendno p-value reported

Results An obvious trend of hypomethylation was observed within the whole genome of Pre 30 dairy cows.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.