Barely Significant
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Semaglutide and tirzepatide effects on cardiovascular outcomes in people with overweight or obesity in the real world (STEER).

Diabetes Obes Metab · 2026 · PMC12890754 · PMID 41491349

1
hedged sentence
0.0910
closest p · 1.8× alpha
0.0910
boldest claim

The sentences

did not reach statistical significancep = 0.091so close (0.05 < p ≤ 0.1)
3.2 MACE outcomes The differences in MACE‐3, which included CV‐related mortality instead of all‐cause mortality, did not reach statistical significance (HR 0.74; 95% CI 0.52–1.05; p = 0.091; Figure 3A ).

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