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From Classical to Emerging Biomarkers of Brain and Central Nervous System Tumors. An Evidence-Based Review with a Focus on Gliomas.

Cell Mol Neurobiol · 2026 · PMC12891329 · PMID 41579222

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Elevated preoperative cfDNA levels (> 13.4 ng/mL) and detection of somatic mutations in plasma were associated with shorter PFS and OS, though some associations did not reach statistical significance (Bagley et al. 2019 ).

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