Immunohistochemical expression of Ki-67, estrogen receptor, and human epidermal growth factor receptor 2 in p16-positive premalignant and malignant cervical squamous lesions: associations with clinicopathological parameters.

Ewha Med J · 2026 · PMC12891606 · PMID 41668229

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did not reach statistical significanceno p-value reported

ER expression was observed to decrease with lesion progression; however, this trend did not reach statistical significance in the present study.

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an increasing trendno p-value reported

The intensity and grade of p16 expression showed an increasing trend with advancing lesion severity ( Table 1 ).

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