Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross-Species Multi-Cohort Bioinformatic Study.

Although the association did not reach statistical significance (Fisher's exact p = 0.068, OR = ∞, 95% CI = [0.59–Inf]), these data indicate a potential link between EDY and an increased risk for malignant progression. 3.3 LOY in Men With OPMD As EDY is mainly a consequence of LOY, an OPMD cohort for which genomic and clinical follow‐up data were available was analyzed (Amsterdam UMC cohort, Figure 2E ).

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