Epicardial adipose tissue mediates the association between circulating hsa-miR-4750-3p and coronary artery disease in patients with type 2 diabetes mellitus.

The integration of EAT thickness with miRNA expression (model 4) substantially enhanced predictive power, resulting in a higher AUC of 0.988 compared to models 1–3 ( p = 0.013, p = 0.004, and p = 0.026, respectively), as well as miRNA-based model (AUC = 0.959) [ 18 ], but this improvement did not reach statistical significance ( p = 0.240).

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