A New Gold Standard? Impact of Broad-spectrum Penicillin-based Antibiotic Prophylaxis on Outcome After Pancreatoduodenectomy: Results of a Systematic Review and Meta-analysis (PROSPERO CRD42024559197).

Ann Surg · 2026 · PMC12893182 · PMID 40115985

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a clear trendno p-value reported

Despite the meta-analysis not identifying a clear trend regarding the optimal duration of antibiotic therapy in individuals with or without PBD, there is a lack of robust data from randomized controlled trials supporting extended durations.

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