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Pathologic response and safety of preoperative treatment regimens in gastric cancer undergoing D2 gastrectomy: a real-world cohort study.

Front Immunol · 2026 · PMC12893969 · PMID 41694377

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In the CPS ≥5 subgroup, the ORs for Chemo+IO and Chemo+IO+Targeted vs Chemo were 1.09 (95% CI 0.33–3.61) and 2.67 (95% CI 0.65–10.88), respectively, although numerically higher, these did not reach statistical significance, likely due to limited sample size ( Supplementary Table S3 ).

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