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Novel C-terminal HBx truncation (G135) in genotype D1 HBV: predicted effects on oncogenic signaling.

Infect Agent Cancer · 2026 · PMC12895752 · PMID 41606753

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Although these correlations did not reach statistical significance owing to the limited sample size, the trends suggest a potential association between viral replication and hepatocellular injury.

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a positive trendno p-value reported
A positive trend was observed, suggesting that increased HBV replication may be associated with increased hepatocellular injury.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.