Serum metabolomic profiles linking diabetes mellitus to pulmonary hypertension: a prospective cohort study with mediation analysis and risk prediction.

Respir Res · 2026 · PMC12896080 · PMID 41555368

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did not reach statistical significanceno p-value reported

Although GlycA (HR = 1.043, P FDR =0.247) and glucose (HR = 1.041, P FDR =0.202) did not reach statistical significance in univariate models, its inclusion in multivariable LASSO models improved predictive performance (C-statistic increased from 0.726 to 0.735).

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