Early prediction of pathologic complete response to neoadjuvant chemotherapy based on longitudinal total choline of MR spectroscopy in patients with breast cancer.

BMC Med Imaging · 2026 · PMC12896254 · PMID 41545976

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0610

boldest claim

The sentences

a decreasing trendP < 0.001actually significant

Except for Luminal B ( P = 0.336), the tCho of different molecular subtypes in the pCR group showed a decreasing trend ( P < 0.001).

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did not reach statistical significanceP = 0.061so close (0.05 < p ≤ 0.1)

Although baseline tCho concentration (Cho0) appeared numerically lower in the HER2-enriched and Triple-negative subtypes, the overall difference did not reach statistical significance ( P = 0.061).

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