Epitranscriptomic Regulation of Platinum Resistance via the METTL3-ADAM23 Axis in Ovarian Cancer.

Cells · 2026 · PMC12896498 · PMID 41677656

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did not reach statistical significanceno p-value reported

Consistent with in vitro observations, carboplatin treatment in vivo was associated with a modest increase in Mettl3 expression and a corresponding decrease in Adam23 expression in tumor RNA from the ID8 intraperitoneal mouse model, although these changes did not reach statistical significance ( Supplementary Figure S4C,D ).

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