Acetylcholinesterase Inhibition Reverses Age-Related Pulmonary Decline and Increases Bronchus-Associated Lymphoid Tissue Formation in Aged Mice.

Biology (Basel) · 2026 · PMC12896647 · PMID 41677741

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.1756

boldest claim

The sentences

highly significantp < 0.0001actually significant

In the middle quartiles ( Figure 4 D,E), donepezil-treated aged mice showed highly significant reductions in alveolar size compared to aged controls ( p < 0.0001).

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showed a trendp = 0.1756not close (p > 0.1)

Notably, donepezil-treated aged mice showed a trend toward smaller MAA compared to aged untreated animals, approaching statistical significance ( p = 0.1756).

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