Extracellular Vesicle Associated Proteomic Biomarkers in Breast Cancer: A Systematic Review and Meta-Analysis.

The most enriched components included the cytoplasm (56.6%), exosomes (45.5%), extracellular (30.8%), extracellular region (16.2%), cytoskeleton (15%), and extracellular space (11%), all with highly significant values ( p < 0.001) ( Figure 3 ).

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Other processes, such as spindle assembly, blood vessel development, immune cell migration, coagulation regulation, and development, had very low gene representation (≤0.4%) and did not reach statistical significance ( p = 1). 3.2.

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