Transcription-Coupled Repair Promotes the Retention of Mutations in Coding Regions During Replication Stress.

Int J Mol Sci · 2026 · PMC12896993 · PMID 41683584

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did not reach statistical significanceno p-value reported

However, broader senescence-related annotations (such as Cellular Senescence, SAHF (Senescence-Associated Heterochromatin Foci) formation, or apoptosis-related DNA fragmentation pathways), as well as canonical DNA damage response pathways (including NHEJ and ATM-mediated signaling), did not reach statistical significance under basal conditions.

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