Role of Inositol Hexakisphosphate Kinases in Vascular Smooth Muscle Cell Calcification.

Int J Mol Sci · 2026 · PMC12897964 · PMID 41683831

Europe PMC DOI

hedged sentence

0.0840

closest p · 1.7× alpha

0.0840

boldest claim

The sentences

did not reach statistical significancep = 0.084so close (0.05 < p ≤ 0.1)

Knockdown of IP6K1 did not significantly affect the pro-calcific marker mRNA expression during control conditions, but significantly suppressed ALPL and BMP2 mRNA expression and tended to reduce CBFA1 and BGLAP mRNA expression during calcifying conditions; these differences, however, did not reach statistical significance ( p = 0.084 and p = 0.067, respectively).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.