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Chemoimmunotherapy Combinations in Elderly Patients with Metastatic Non-Small Cell Lung Cancer and PD-L1 Expression < 50%: Results from an Italian Real-World Study.

J Clin Med · 2026 · PMC12898390 · PMID 41682846

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Similarly, in the CheckMate 9LA study, which included 70 patients (10%) aged ≥75 years, the treatment effect did not reach statistical significance and the HR did not favour the experimental arm receiving dual ICI blockade plus chemotherapy (HR 1.21, 95%CI 0.69–2.12) [ 8 ].

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