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Global Leukocyte DNA Methylation Is Associated with Dietary Methyl-Donor Intake and Cardiometabolic Risk in Rheumatoid Arthritis and Control Subjects.

Int J Mol Sci · 2026 · PMC12898410 · PMID 41683996

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Although the association between methionine intake and categorical hypomethylation did not reach statistical significance in fully adjusted logistic models, the consistency observed in continuous analyses supports a modest but independent relationship between dietary methyl-donor intake and global epigenetic status.

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