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Efficacy and safety of sequential hyperthermic intraperitoneal chemotherapy following surgery for pathological T staging 4 gastric cancer.

World J Gastroenterol · 2026 · PMC12898868 · PMID 41695288

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The differences in the latter subgroup did not reach statistical significance, potentially due to the limited sample size; nevertheless, both analyses consistently suggested that HIPEC provided an additional survival benefit when combined with systemic chemotherapy, regardless of the regimen intensity.

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