Comparative Effects of Diet, Exercise, and Pharmacotherapy on Metabolic Syndrome Severity in Overweight and Obese Cohorts: A Systematic Review and Meta-Analysis.

Nutrients · 2026 · PMC12899630 · PMID 41683294

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hedged sentence

0.1340

closest p · 2.7× alpha

0.1340

boldest claim

The sentences

did not reach statistical significancep = 0.134not close (p > 0.1)

Meta-Analyses on Pharmacological Interventions Versus Controls The pooled effect on the MetS z-score did not reach statistical significance (mean difference = −0.07; 95% CI −0.16 to 0.02; p = 0.134; I 2 = 67%; p = 0.017; 5 arms) when pharmacological interventions were compared with controls.

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