Plasma fatty acids reflect pain, disability, and psychological well-being in knee osteoarthritis in a longitudinal study with joint replacement surgery.

Sci Rep · 2026 · PMC12902111 · PMID 41571733

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

borderline significancep = 0.058so close (0.05 < p ≤ 0.1)

In addition, 20:3n-6 was associated with BAI and showed borderline significance with BDI ( p = 0.058), while 18:3n-3 was associated with PSEQ scores (Fig. 3 E–F).

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of borderline significanceno p-value reported

There was a positive association between plasma 20:3n-6 percentages and anxiety scores in the present study that, to the best of our knowledge, has not been previously documented, and the connection between plasma 20:3n-6 and depression was of borderline significance.

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did not reach statistical significanceno p-value reported

We observed inverse correlations between very-long-chain SFAs, 24:1n-9, and femoral and tibial cartilage thicknesses, but these data did not reach statistical significance in the univariate ANOVAs adjusted for age and BMI.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.