5-ALA vs. fluorescein guided resection for high-grade gliomas: A systematic review and meta-analysis.

Mol Clin Oncol · 2026 · PMC12902751 · PMID 41695318

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP=0.06so close (0.05 < p ≤ 0.1)

In the study by Hansen et al ( 37 ), median OS was longer in the fluorescein group (19.7 months) compared with the 5-ALA group (14.8 months), though this difference did not reach statistical significance (P=0.06).

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