Greater locus coeruleus vulnerability in atypical clinicopathologic forms of Alzheimer's disease.

Alzheimers Dement · 2026 · PMC12902885 · PMID 41685552

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did not reach statistical significanceno p-value reported

Hippocampal sparing AD cases had a smaller area (0.71 mm 2 [0.42,0.93]) compared to typical (0.87 mm 2 [0.56,1.3]) and limbic predominant AD cases (0.98 mm 2 [0.45,1.3]) in the rostral LC, although differences in area did not reach statistical significance (Figures 1 and S3 ).

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