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Human iPSC-derived neural progenitor cells rescue motor function and brain pathology in symptomatic Canavan disease mice.

Stem Cell Reports · 2026 · PMC12903093 · PMID 41576940

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CD#68 ASPA iNPC-transplanted CD (Nur7) mice exhibited a trend toward increased grip strength at 3 months post-transplantation, but the improvement did not reach statistical significance until 6 months post-transplantation ( Figures 6 B and 6D).

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