The impact of clade B lineage 5 MERS coronaviruses spike mutations from 2015 to 2023 on virus entry and replication competence.

PLoS Pathog · 2026 · PMC12904574 · PMID 41632817

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

did not reach statistical significancep = 0.058so close (0.05 < p ≤ 0.1)

The minor reduction trend in 2023/B5-3 did not reach statistical significance (p = 0.058).

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a decreasing trendno p-value reported

The number of reported human cases has been on a decreasing trend since 2016 and reached a nadir during the COVID-19 pandemic.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.