Barely Significant
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MET alterations are enriched in lung adenocarcinoma brain metastases, defining a distinct biologic subtype.

J Clin Invest · 2026 · PMC12904726 · PMID 41411048

Europe PMCDOI
1
hedged sentence
0.1900
closest p · 3.8× alpha
0.1900
boldest claim

The sentences

did not reach statistical significanceP = 0.19not close (p > 0.1)
Other genes that were more frequently mutated in MET -altered LUAD BMs but did not reach statistical significance included CDKN2A (16% vs. 7%; P = 0.19), RET (16% vs. 9%; P = 0.29), ABL1 (13% vs. 2%; P = 0.09), IDH1 (10% vs. 0%; P = 0.07), and ALK (10% vs. 5%; P = 0.35).

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