Pachymic Acid Targets PI3K/Akt Signaling Pathway to Attenuate tPA-Induced Hemorrhagic Transformation After Ischemic Stroke.

CNS Neurosci Ther · 2026 · PMC12905004 · PMID 41689208

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showed a trendno p-value reported

Western blot analysis revealed that compared with the Sham group, the expression of p‐PI3K and p‐Akt was significantly reduced in the MCAO/R groups and showed a trend of further reduction after tPA treatment (Figure 6B,C ).

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