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Comprehensive metabolic profiling across five lifespan stages in murine hippocampus and cortex reveals sex-related variation in age-related cognitive decline.

Commun Biol · 2026 · PMC12905236 · PMID 41554987

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In the elderly stage, carnosine levels showed a trend of reduction in these two regions in both females and males, suggesting a potential decrease in antioxidative activity and transition into a decompensatory phase.

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