Caspofungin enhances antifungal immunity in human blood through transcriptional reprogramming.

Notably, at 8 h post-infection , IFN-γ secretion already showed an upward trend in the ECH S /FKS wt strain upon CAS treatment (CAS+/CAS−: 119 ± 4.2%), although this difference did not reach statistical significance, while no such trend was observed for the resistant strain (99.6 ± 25.6%) (Fig. 2E ).

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