Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6<sup>+</sup>CD8<sup>+</sup> T cell anti-tumor activity.

PeerJ · 2026 · PMC12906710 · PMID 41700134

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

showed a trendno p-value reported

Furthermore, among MMRp patients, elevated GSVA scores for CXCR6 + CD8 + T cells showed a trend toward improved prognosis.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6&lt;sup&gt;+&lt;/sup&gt;CD8&lt;sup&gt;+&lt;/sup&gt; T cell anti-tumor activity.

The sentences

Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6<sup>+</sup>CD8<sup>+</sup> T cell anti-tumor activity.