Longitudinal metagenomics reveals continuous restructuring of soil pathobiome under persistent <i>Phytophthora</i> pressure.

Genes were categorized into highly significant ( p < 0.001 and log 2 FC > 2), very significant ( p < 0.01 and log 2 FC > 1.5), significant up ( p < 0.05 and log 2 FC > 1.0), significant down (p < 0.05 and log 2 FC < -1.0), marginally significant ( p < 0.1 ) and not significant ( p ≥ 0.1 ).

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Functional profiling analysis exhibited systematic metabolic adaptation, with a clear trend toward enrichment of core biosynthetic processes and microbial coordination.

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Our analysis uncovered profound microbial restructuring, beginning with cumulative transcriptional reprogramming of highly significant genes.

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