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Balancing Demineralisation and Collagen Integrity: A Nanoscale Analysis of Etching Time in Human Dentin.

Int Dent J · 2026 · PMC12907654 · PMID 41653833

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Although differences between the 10- and 15-second groups did not reach statistical significance, the subtle reduction in D-banding periodicity and early signs of fibrillar disorganisation observed at 15 seconds may reflect the initial stages of collagen structural alteration associated with extended acid exposure.

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