A systematic review and meta-analysis on surgery for lumbar disc herniation: optimal timing of surgery, return to work and outcomes compared with conservative management.

Although early surgery was associated with a numerically greater reduction in leg pain compared with delayed surgery, the pooled random-effects estimate did not reach statistical significance (pooled MD −1.05 on a 0–10 scale, 95 % CI −2.41 to 0.31).

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