Causality between appendiceal disease and cancers of the digestive system: A Mendelian randomization study.

Medicine (Baltimore) · 2026 · PMC12908837 · PMID 41686625

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hedged sentence

0.0780

closest p · 1.6× alpha

0.0780

boldest claim

The sentences

did not reach statistical significanceP = .078so close (0.05 < p ≤ 0.1)

On the other hand, malignant neoplasms of the liver and intrahepatic bile ducts were more common among individuals with appendiceal disease; however, the association did not reach statistical significance (OR = 1.967, 95% CI: 0.926–4.176, P = .078, by the IVW method) (Fig. 2 ).

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