Efficacy of esketamine on perioperative anxiety in patients receiving anesthesia: a systematic review and meta-analysis of RCTs.

Front Psychiatry · 2026 · PMC12909511 · PMID 41710108

Europe PMC DOI

hedged sentence

0.2180

closest p · 4.4× alpha

0.2180

boldest claim

The sentences

did not reach statistical significancep = 0.218not close (p > 0.1)

Visual examination of the funnel plot indicated a mild possibility of publication bias ( Figure 3A ), although Egger’s regression analysis did not reach statistical significance (p = 0.218). 3.2.2.

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