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Multifunctional pectin derivatives as anticancer agents in colorectal cancer via synthesis, computational insights, and modulation of NRF2/HO-1, HIF-1α, and VEGF/PDGF-D signaling pathways.

Sci Rep · 2026 · PMC12910068 · PMID 41688504

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Docking studies of the 1n3u protein with Pectin derivatives indicate a clear trend of increasing binding affinity and stability with chemical modification of the ligands (Fig. 9 B).

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