Barely Significant
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Simple appendectomy is a safe and effective surgical approach for low-grade appendiceal mucinous neoplasm at the appendiceal root with negative margins: a retrospective comparative cohort study.

World J Surg Oncol · 2026 · PMC12910778 · PMID 41566517

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a significant trendno p-value reported
Large tumor volume [HR = 2.218; P = 0.001] and late tumor T stage [HR = 7.715; P = 0.015] were the predictive factors retained in the final RFS model; The increase of serum CA12−5 [HR = 8.852; P = 0.065] was not statistically significant, but it did show a significant trend.

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