While a high dose of PMN-MDSCs (>8,000/μL) was associated with a strong trend towards lower relapse and significantly better 300-day leukemia-free survival (LFS) (Table 3 ), the most striking effect was observed for the LOX-1+ PMN-MDSC subset.
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Infused PMN-MDSCs from G-CSF-mobilized PBSCs protect against II-IV° acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
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