Polygenic risk scores improve CAD risk prediction in individuals at borderline and intermediate clinical risk.

NPJ Cardiovasc Health · 2025 · PMC12912298 · PMID 41775875

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did not reach statistical significanceno p-value reported

The caIRS also outperformed the baseline PCE model when using lower classification thresholds of 7.5% and 10%, with the exception of the MESA cohort where the overall NRI did not reach statistical significance (Supplementary Table 1 ).

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