Interaction effects of sedentary behavior and depression on MAFLD in NHANES 2017-2020 and 2021-2023.

PLoS One · 2026 · PMC12912620 · PMID 41701718

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did not reach statistical significanceno p-value reported

While the interaction effect did not reach statistical significance with a 95% confidence interval (CI) across all BMI subgroups (consistent with the conservative nature of 95% CI for common outcomes), the 90% CI confirmed a meaningful additive interaction in overweight participants (RERI = 0.318, 90% CI: 0.036 ~ 0.600; AP = 0.223, 90% CI: 0.182 ~ 0.263; S=1.310, 90% CI: 1.000 ~ 1.620).

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