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Real-world sinonasal outcomes in patients with primary diffuse chronic rhinosinusitis treated with mepolizumab across polyp phenotypes.

Front Immunol · 2026 · PMC12913089 · PMID 41716394

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While median SNOT-22 scores numerically improved in both subgroups post mepolizumab therapy, these changes did not reach statistical significance, likely reflecting limited sample size, heterogeneous follow-up timing, and missing data.

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