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Mutational insights and <i>in silico</i> characterization of <i>NEK</i> family kinases in OSCC patients from the Pakistani population.

Front Bioinform · 2025 · PMC12913394 · PMID 41716219

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showed a trendno p-value reported
Our findings that NEK10- mutant patients exhibited a significantly better overall survival (p < 0.05), whereas mutations in NEK1 , NEK2 , NEK5 , and NEK9 showed non-significant trends toward improved survival, and mutations in NEK4 and NEK8 showed a trend toward worse survival are consistent with a context‐dependent dual role of NEKs in tumorigenesis.

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