Comparing metabolic syndrome parameters, oxidative stress, cellular metabolism, and gene polymorphism between people with schizophrenia and healthy controls.

Front Psychiatry · 2026 · PMC12913418 · PMID 41717560

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0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

did not reach statistical significancep = 0.054so close (0.05 < p ≤ 0.1)

Subgroup analysis based on GCLC GAG TNR genotypes revealed that schizophrenia patients with high-risk genotypes (8/8, 8/9, 9/9) had higher MDA levels than those with low-risk genotypes (7/7, 7/9; 0.476 ± 0.197 nmol/mL), although the difference approached but did not reach statistical significance ( p = 0.054).

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