LOAd703-induced tumor microenvironment gene engineering in combination with atezolizumab in metastatic malignant melanoma: a phase I/II trial.

Nat Commun · 2026 · PMC12913765 · PMID 41698954

Europe PMC DOI

hedged sentence

0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

near statistical significancep = 0.075so close (0.05 < p ≤ 0.1)

In univariate Cox regression analysis, no clinical parameters were associated with OS except for ECOG status at enrollment that was near statistical significance ( p = 0.075) as well as receiving four or five previous treatments ( p = 0.065 and p = 0.083 , respectively; Supplementary Table 8 ).

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