Reduced expression of BIRC2 and BIRC3 associated with longer survival in pediatric high-grade gliomas.

Sci Rep · 2026 · PMC12913816 · PMID 41617829

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0820

boldest claim

The sentences

a negative trendp > 0.05actually significant

For BIRC3 , although the OR values also suggested a negative trend (OR range 0.24–0.44), none of the analyzed associations reached statistical significance ( p > 0.05) (Fig. 14 ).

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borderline significancep = 0.082so close (0.05 < p ≤ 0.1)

PD-1 high expression (score 2–3) was associated with shorter OS compared with PD-1 low (score 0–1) with borderline significance (log-rank p = 0.082).

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