cfGWAS reveal genetic basis of cell-free DNA end motifs.

Although the difference did not reach statistical significance, we do observe a trend of increased cfDNA concentration of PANX1 KO cells (mean fold change: 1.10, range: 1.05–1.15) compared to the WT cells (mean fold change:1.00, range: 0.86–1.10, t (8) = 2.10, p -value = 6.89e−02, mean difference = 0.098, 95% CI = [−0.0096, 0.2065]) (Supplementary Fig. 11B ).

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