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Effectiveness and safety of cyclosporine A in moderate to severe COVID-19: a randomized, open-label trial.

Sci Rep · 2026 · PMC12913897 · PMID 41702946

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showed a trendno p-value reported
A retrospective study indicated that cyclosporine A (CsA) may reduce mortality in patients with severe COVID-19 52 .In a pilot randomized clinical trial, CsA showed a trend toward increasing the proportion of COVID-19 patients without interstitial lung disease at 3 months, including both those who did and did not require IMV 53 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.