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The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung.

Respir Res · 2005 · PMC1291407 · PMID 16266428

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In our study the positive correlation between total number of macrophages and nitrite failed to reach statistical significance, suggesting the involvement of an additional cellular source of NO in response to silica, such as alveolar type II epithelial cells (35).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.